The NCD Alliance united to put non-communicable diseases (NCDs) on the global agenda. Since its inception in 2009, one of its key campaign objectives has been the inclusion of NCDs in the successors to the Millennium Development Goals (MDGs). The UN High-Level Meeting on NCDs in September 2011 affirmed NCDs are one of the major challenges for development in the 21st century. Now, with the expiry date of the current MDGs fast approaching, the NCD community has a unique opportunity to build on the momentum from the UN NCD Summit, and ensure that NCD prevention and control is central to the sustainable development agenda for the next fifteen years. There is growing political consensus and strong technical foundations for the inclusion of NCDs in the post-2015 development agenda. But in these last six months of the process, coordinated and effective advocacy at national and regional levels is essential to maintain the pressure.